Canadian Health Care Mall presents you the way out if Viagra and Cialis don’t work exactly – Levitra, medication in the same category.
Levitra: Brief History
Erectile dysfunction has become one of the most common male diseases. Its appearance can be caused not only by physiological factors. In recent years scientists are more frequently associated impotence development with life rhythm acceleration, psychological stress increase, and pollution. Earlier erectile dysfunction was a disorder of elderly men, but today, even very young boys often have erection problems. This has prompted pharmaceutical companies to develop specialized medicines.
The pioneer was Viagra. The FDA approved this drug in 1998. Then Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough have begun together to develop a new active component – Vardenafil. The development process was promising, and soon a new drug was introduced into the pharmaceutical market. It turned out to be milder than Viagra. The list of most popular queries in search engines was supplemented by such phrases as «Levitra bestselling», «buy Levitra», «order Levitra” and so forth. In 2005 in most markets outside Italy and the United States, the right to sell medicines was repurchased by Bayer Company. GlaxoSmithKline is selling this drug under the name “Vivanza”.
As you can guess this drug has been created in case if Viagra and Cialis don’t work. It has the same duration effect as sildenafil but considered to be milder. Canadian Health Care Mall offers you Levitra at an attractive price – $1,82 per item.
Description of the drug
Before to give you Levitra 20 mg description, let’s remember how erection appears. This hemodynamic process is completely dependent on smooth muscles relaxation located in the base of the penis and prevents blood outflow. During sexual stimulation cavernous bodies, nerve endings start to allocate nitrogen monoxide (NO), which stimulates guanylate cyclase enzyme production. Together with NO, it is converted into cyclic guanosine monophosphate. This substance promotes penile smooth muscles relaxation. As a result, blood begins to flow through arteries to cavernous bodies. They are like a sponge absorbing blood and provoking size increase.
When is Levitra Used?
In case of erectile function violation, the natural process of genital system excitement interferes with another enzyme – phosphodiesterase 5 type. It destroys nitric oxide, which ultimately leads to lack of erection. Active ingredient -Vardenafil belongs to an inhibitor of PDE-5. It blocks enzyme action, allowing erection proceed further smoothly. This medicine does not affect other types of phosphodiesterase. For many men to restore potency half-dose (10 mg) is enough. It is necessary to clarify that drug restores natural mechanism of erection. Therefore, without sexual stimulation, Levitra won’t have any effect at all.
Mechanism of Action
Entering body, Levitra is fast absorbed. If you take medication on an empty stomach, maximum levels of an active substance in the blood reach after 15 minutes. But in most cases, the peak is observed in an average of 45-60 minutes. If the drug enters the body together with a large amount of food, it will begin to operate with delay.
The active constituent- Vardenafil – powerful inhibitor of PDE-5. Thanks to modern technology highly selective drug action are achieved. Due to it, side effects probability is minimized as well. Blocking phosphodiesterase leads to stable, sustainable erection. In one study, the drug was used in 10 mg dosage. The researchers aimed to examine vardenafil effectiveness at a reduced dose. The results showed that even this active component amount (10 mg) has helped to achieve an erection at 90% of patients.
Levitra for Women
Levitra action for women is hardly been studied. Anatomists and physiologists have repeatedly pointed out the fact that genital organs structure and excitement mechanism in men and women have many features in common. However, clinical trials of drug effect were conducted in men only. Although there is evidence that many women take 5mg before sexual intercourse. They claim that after taking this medication orgasm strength is greatly increased. But to prove the effect of this drug for women it is necessary to carry out more trials.
Levitra and Alcohol
Can you drink alcohol with Levitra simultaneously? Alcohol according to drug- manufacturers has no effect on vardenafil speed and effectiveness. However, we must understand that by themselves alcoholic beverages do not contribute to potency strengthening. A small amount of alcohol (eg, 3-4 glasses of wine or 2-3 glasses of whiskey) did not have an impact on the drug action as well as an erection. But it can slow down effect appearance.