Before to give you Levitra 20 mg description, let’s remember how erection appears. This hemodynamic process is completely dependent on smooth muscles relaxation located in the base of the penis and prevents blood outflow. During sexual stimulation cavernous bodies, nerve endings start to allocate nitrogen monoxide (NO), which stimulates guanylate cyclase enzyme production. Together with NO, it is converted into cyclic guanosine monophosphate. This substance promotes penile smooth muscles relaxation. As a result, blood begins to flow through arteries to cavernous bodies. They are like a sponge absorbing blood and provoking size increase.
In case of erectile function violation, the natural process of genital system excitement interferes with another enzyme – phosphodiesterase 5 type. It destroys nitric oxide, which ultimately leads to lack of erection. Active ingredient -Vardenafil belongs to an inhibitor of PDE-5. It blocks enzyme action, allowing erection proceed further smoothly. This medicine does not affect other types of phosphodiesterase. For many men to restore potency half-dose (10 mg) is enough. It is necessary to clarify that drug restores natural mechanism of erection. Therefore, without sexual stimulation, Levitra won’t have any effect at all.
Entering body, Levitra is fast absorbed. If you take medication on an empty stomach, maximum levels of an active substance in the blood reach after 15 minutes. But in most cases, the peak is observed in an average of 45-60 minutes. If the drug enters the body together with a large amount of food, it will begin to operate with delay.
The active constituent- Vardenafil – powerful inhibitor of PDE-5. Thanks to modern technology highly selective drug action are achieved. Due to it, side effects probability is minimized as well. Blocking phosphodiesterase leads to stable, sustainable erection. In one study, the drug was used in 10 mg dosage. The researchers aimed to examine vardenafil effectiveness at a reduced dose. The results showed that even this active component amount (10 mg) has helped to achieve an erection at 90% of patients.
Levitra action for women is hardly been studied. Anatomists and physiologists have repeatedly pointed out the fact that genital organs structure and excitement mechanism in men and women have many features in common. However, clinical trials of drug effect were conducted in men only. Although there is evidence that many women take 5mg before sexual intercourse. They claim that after taking this medication orgasm strength is greatly increased. But to prove the effect of this drug for women it is necessary to carry out more trials.
Can you drink alcohol with Levitra simultaneously? Alcohol according to drug- manufacturers has no effect on vardenafil speed and effectiveness. However, we must understand that by themselves alcoholic beverages do not contribute to potency strengthening. A small amount of alcohol (eg, 3-4 glasses of wine or 2-3 glasses of whiskey) did not have an impact on the drug action as well as an erection. But it can slow down effect appearance.