Leukotriene antagonists may be applied with caution and only according to stringent prescription. «B» category of safety.
Drugs prescribed only individually, this rule should especially be followed during pregnancy. The dosage for treatment required for a given the severity degree is determined by the doctor, which observes the patient, guided, in addition to anamnesis, by peakflowmetry data.
Bronchial asthma is one of those diseases that require patient’s ability to control his condition. Just like at hypertension a patient needs tonometer, and at diabetes (http://www.diabetes.org/) — blood glucose monitor, for self-monitoring at asthma a portable and easy-to-use device was created — PEF meter.
Recorded indicator — peak expiratory flow rate, abbreviated as PEF — allows disease state monitoring at home.
It is advised to register indicators twice a day, in the morning and evening, before applying bronchodilators, and also on symptoms onset. Data is recorded in the form of a diagram, as it gives more information: not only specific numbers are important, but also the shape of the resulting graph. One of the alarming symptoms are «morning gaps»: periodically registered low indications in early morning hours. «Morning gaps» are a sign of incomplete control of this disorder and early symptom of impending recrudescence.
There are still no actual changes in the state of health during this period, and timely undertaken measures prevent exacerbation development. Self-control with PEF meter is an essential requirement for making an action plan: detailed doctor recommendations, which describe basic therapy and necessary actions in case of the state of health changes.
Watch the video to create an action plan:
The most important thing is to try to prevent recrudescences. Measures for limiting contacts with allergens and proper basic therapy greatly reduces risks. But recrudescences still occur, and the most common cause is ARVI.
Asthma recrudescence is dangerous not only for mother but it also is a serious threat to the fetus because of hypoxia, so treatment must not be delayed. Recrudescences treatment requires nebulizer (albuterol). The treatment effect is evaluated not only clinically, but also with PEF meter: if after treatment indicators have not reached 70% level of normal (or better for a given patient) urgent hospitalization is required. If necessary, nebulizer therapy can be combined with inhaled anticholinergic drugs, with little effect aminophylline is prescribed intravenously. To prevent fetal hypoxia oxygen therapy is applied. At severe asthma recrudescences systemic hormonal agents are used, including tabletted hormones in short course; however avoid triamcinolone drugs because of mother and fetus muscular system impact risk, and also dexamethasone and betamethasone; prednisolone and methylprednisolone drugs are preferred. The harm that hypoxia does to the child is many times greater than possible side effects.
As it was already mentioned, during pregnancy it is absolutely contraindicated to use any ephedrine drugs, as it exacerbates fetal hypoxia. Adrenaline during its recrudescences is also not recommended.